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Image Search Results
Journal: Analytical Chemistry
Article Title: Evolution and Impact of Nucleic Acid Amplification Test (NAAT) for Diagnosis of Coronavirus Disease
doi: 10.1021/acs.analchem.3c05225
Figure Lengend Snippet: Schematic representation of (a) SARS-Cov-2 virion and its structural protein (b) spike protein denoting S1 and S2 subunit and its binding with ACE2 receptor. [Created with BioRender.com .]
Article Snippet: SARS-CoV-2 MassArray Test and Ethos Laboratories SARS-CoV-2 MALDI-TOF Assay , employed the
Techniques: Binding Assay
Journal: Analytical Chemistry
Article Title: Evolution and Impact of Nucleic Acid Amplification Test (NAAT) for Diagnosis of Coronavirus Disease
doi: 10.1021/acs.analchem.3c05225
Figure Lengend Snippet: Schematic representation of the SARS-CoV-2 genome, which includes a single-stranded RNA having various Open Reading Frames (ORF1a, ORF1b, ORF3a, ORF3b, ORF6, ORF7a, ORF7b, ORF8a, ORF8b, ORF9b), leading to the formation of 16 nonstructural protein (nsps1–nsps16), structural proteins like S (spike protein) having the S1 subunit, which includes NTD, RBD, SD1, and SD2 and the S2 subunit, which contains FL, HR1, HR2, and TM. Other structural proteins are E (Envelop protein), M (Membrane protein), N (Nucleocapsid protein). PL-pro (papain-like protease), and 3CL-pro (cysteine proteases). [Created with BioRender.com .]
Article Snippet: SARS-CoV-2 MassArray Test and Ethos Laboratories SARS-CoV-2 MALDI-TOF Assay , employed the
Techniques: Membrane
Journal: medRxiv
Article Title: Comparison of SARS-CoV-2 detection in Saliva by real-time RT-PCR and RT-PCR/MALDI-TOF Methods
doi: 10.1101/2021.03.11.21253234
Figure Lengend Snippet: Linear regression of commercial standard in negative NP matrix run alongside three dilutions of pooled positive SARS-CoV-2 NP clinical specimens. (A) Mean (±SEM) Roche target T1 Ct values and (B) target T2 Ct values of seven serial dilutions of commercial standard plotted with lines of best fit. Correlation coefficients and p-values are annotated for each standard curve. Concentrations for three dilutions (D1, D2, D3) of in-house standard were extrapolated from T1 and T2 lines of best fit (dotted green lines) to determine the concentration of the in-house standard.
Article Snippet: Here, we compared two methods for SARS-CoV-2 detection in saliva: the Roche cobas® 6800/8800 SARS-CoV-2 real-time RT-PCR Test and the
Techniques: Concentration Assay
Journal: medRxiv
Article Title: Comparison of SARS-CoV-2 detection in Saliva by real-time RT-PCR and RT-PCR/MALDI-TOF Methods
doi: 10.1101/2021.03.11.21253234
Figure Lengend Snippet: Scatter plots depict the number of SARS-CoV-2 targets on the Agena platform detected and the corresponding Roche cycle threshold (Ct) for each clinical saliva specimen. (A) Ct values for Roche target T1 (Orf1ab) and (B) Roche target T2 (E gene) are depicted for individual clinical saliva specimens. Medians are depicted in each column. Statistically significant differences are depicted (e.g., *, p<0.05; **, p<0.01; ***, p<0.001, ****, p<0.0001) based on student’s t-test or Mann-Whitney non-parametric test depending on whether data was normally distributed (see Methods).
Article Snippet: Here, we compared two methods for SARS-CoV-2 detection in saliva: the Roche cobas® 6800/8800 SARS-CoV-2 real-time RT-PCR Test and the
Techniques: MANN-WHITNEY
Journal: Diagnostics (Basel, Switzerland)
Article Title: Rapid Evaluation of the Xpert ® Xpress CoV-2 plus and Xpert ® Xpress CoV-2/Flu/RSV plus Tests.
doi: 10.3390/diagnostics13010034
Figure Lengend Snippet: Figure 2. Regression analysis of the Xpert® Xpress SARS-CoV-2, Xpert® Xpress CoV-2 plus and Xpert® Xpress CoV-2/Flu/RSV tests, including the equation of the line and R2 values. (a) Xpert®
Article Snippet: These specimens were selected by COVID-19 wave and were previously genotyped by the AllPlex SARS-CoV-2 Variants I and II and NovaPlex SARS-CoV-2 Variants V tests (all Seegene, Seoul, Republic of Korea) and/or TaqMan SARS-CoV-2 Mutation Panels (Thermo Fisher Scientific, Waltham, MA, USA) and/or
Techniques:
Journal: Diagnostics
Article Title: Rapid Evaluation of the Xpert ® Xpress CoV-2 plus and Xpert ® Xpress CoV-2/Flu/RSV plus Tests
doi: 10.3390/diagnostics13010034
Figure Lengend Snippet: ( a ) Xpert ® Xpress CoV-2 plus workflow and ( b ) Xpert ® Xpress CoV-2/Flu/RSV plus workflow. 2 o : secondary; LOD: limit of detection; n: number; SOC: standard of care; VOC: SARS-CoV-2 variants of concern.
Article Snippet: These specimens were selected by COVID-19 wave and were previously genotyped by the
Techniques:
Journal: Diagnostics
Article Title: Rapid Evaluation of the Xpert ® Xpress CoV-2 plus and Xpert ® Xpress CoV-2/Flu/RSV plus Tests
doi: 10.3390/diagnostics13010034
Figure Lengend Snippet: Regression analysis of the Xpert ® Xpress SARS-CoV-2, Xpert ® Xpress CoV-2 plus and Xpert ® Xpress CoV-2/Flu/RSV tests, including the equation of the line and R 2 values. ( a ) Xpert ® Xpress SARS-CoV-2 and Xpert ® Xpress CoV-2 plus ; ( b ) Xpert ® Xpress CoV-2/Flu/RSV plus .
Article Snippet: These specimens were selected by COVID-19 wave and were previously genotyped by the
Techniques: